Assessment and comparison of serum biochemical parameters of Brucella infected and healthy ewes

The present study was undertaken to assess and compare the serum biochemical parameters of healthy ewes and ewes infected with Brucella. A total of forty blood samples were collected from the sheep of different flocks in villages nearby College of Veterinary Science, Korutla in which the abortions were frequent. Blood samples were screened for brucellosis by Rose Bengal Plate Test and later analyzed for serum biochemical parameters like total protein, globulin, albumin, glucose, blood urea nitrogen, Aspartate transaminase and Alanine transaminase. Ten samples gave positive result whereas the remaining thirty samples gave negative result for brucellosis. The results of biochemical parameters shown that globulin, cholesterol, Aspartate transaminase and Alanine transaminase significantly (P<0.05) increased whereas albumin and glucose significantly decreased (P<0.05) in Brucella infected ewes compared to healthy ewes. Total protein and blood urea nitrogen concentrations in the serum decreased in Brucella infected ewes compared to healthy ewes though significance (P<0.05) was not found. These changes in blood biochemical parameters indicate that brucellosis causes deteriorative effects on health of ewes infected with Brucella.